Pericardial patch repair of the left atrioventricular valve in atrioventricular septal defect: long-term changes in the patch

• Published in: Cardiovascular pathology 2009-03, Vol.18 (2), p.119-122
• Main Authors: Luk, Adriana, Ahn, Eric, Soor, Gursharan S, Williams, William G, Mezody, Melitta, Butany, Jagdish
• Format: Article
• Language: English
• Subjects: Adult; Animals; Atrioventricular septal defect; Bovine pericardial patch; Calcinosis; Cattle; Female; Heart Septal Defects, Atrial - surgery; Heart Septal Defects, Ventricular - surgery; Heart Valve Prosthesis; Heart Valve Prosthesis Implantation - methods; Heart Valves - pathology; Heart Valves - surgery; Humans; Mitral valve insufficiency and repair; Pathology; Pericardium - surgery; Pericardium - transplantation; Polyethylene Terephthalates; Reoperation; Transplantation, Heterologous; Treatment Outcome
• ISSN: 1054-8807; 1879-1336
• DOI: 10.1016/j.carpath.2007.12.006

Abstract A 31-year-old woman with partial atrioventricular septal defect underwent left atrioventricular valve (LAVV) replacement. Her initial repair was at 8 years of age. At 23 years of age, she underwent reoperation due to a combination of severe left ventricular outlet obstruction and moderate LAVV regurgitation. At that reoperation, she had a Dacron patch enlargement of the infundibular septum and repair of her LAVV with a xenograft (bovine) pericardial patch sutured into the superior bridging leaflet. LAVV replacement was required 8 years later because of valve insufficiency. There was a perforation in the patch with fibrosis, thickening due to pannus, and calcification of the pericardial tissue and the leaflet tissue, leading to stiffening of the tissue.