Dobutamine stress MRI. Part II. Risk stratification with dobutamine cardiovascular magnetic resonance in patients suspected of myocardial ischemia

The aim of this study was to determine the prognostic value of dobutamine cardiovascular magnetic resonance (CMR) in patients suspected of myocardial ischemia. Clinical data and dobutamine-CMR results were analyzed in 299 consecutive patients. Follow-up data were analyzed in categories of risk level...

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Bibliographic Details
Published in:European radiology 2004-11, Vol.14 (11), p.2046-2052
Main Authors: Kuijpers, Dirkjan, van Dijkman, Paul R M, Janssen, Caroline H C, Vliegenthart, Rozemarijn, Zijlstra, Felix, Oudkerk, Matthijs
Format: Article
Language:English
Subjects:
Cardiotonic Agents
Cardiovascular disease
Dobutamine
Exercise Test - methods
Female
Follow-Up Studies
Heart attacks
Humans
Ischemia
Magnetic Resonance Imaging - methods
Male
Middle Aged
Myocardial Ischemia - diagnosis
Myocardial Ischemia - mortality
Myocardium - pathology
Predictive Value of Tests
Prospective Studies
Risk Assessment - methods
Survival Analysis
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Summary:The aim of this study was to determine the prognostic value of dobutamine cardiovascular magnetic resonance (CMR) in patients suspected of myocardial ischemia. Clinical data and dobutamine-CMR results were analyzed in 299 consecutive patients. Follow-up data were analyzed in categories of risk levels defined by the history of coronary artery disease and presence of rest wall motion abnormalities (RWMA). Major adverse cardiac events (MACE) as evaluated end points included cardiac death, nonfatal myocardial infarction and clinically indicated coronary revascularization. Follow-up was completed in 214 (99%) patients with a negative dobutamine-CMR study (no signs of inducible myocardial ischemia) with an average of 24 months. The patients with a negative dobutamine-CMR study and RWMA showed a significantly higher annual MACE rate (18%) than the patients without RWMA (0.56%) ( P
ISSN:0938-7994
1432-1084
DOI:10.1007/s00330-004-2426-x