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An algorithm to calculate the NMR signal of a multi spin-echo sequence with relaxation and spin-diffusion

An algorithm to calculate NMR signals of a multi-echo pulse sequence with arbitrary position dependent B 0 and B 1 fields taking into account relaxation and spin-diffusion is presented. The multi-echo pulse sequence consists of an initial RF pulse (“90°” RF pulse) and a series of L refocusing RF pul...

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Bibliographic Details
Published in:Journal of magnetic resonance (1997) 2004-11, Vol.171 (1), p.97-106
Main Author: Zur, Yuval
Format: Article
Language:English
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Summary:An algorithm to calculate NMR signals of a multi-echo pulse sequence with arbitrary position dependent B 0 and B 1 fields taking into account relaxation and spin-diffusion is presented. The multi-echo pulse sequence consists of an initial RF pulse (“90°” RF pulse) and a series of L refocusing RF pulses with arbitrary phases and flip-angles. The calculation is exact and takes into account all the magnetization pathways that contribute to the signal on a predefined spatial grid. The theoretical prediction is verified experimentally using a high field NMR microscopy system. The algorithm was implemented in a simulation program in order to optimize the design of an inside-out MR intra-vascular catheter that is used for characterization of vessel wall tissue. Measured data obtained with the catheter are in good agreement with the theoretical prediction of the simulation.
ISSN:1090-7807
1096-0856
DOI:10.1016/j.jmr.2004.07.018