Results and lessons learned from a small medical abortion clinical study in Turkey

This article presents results from a small, introductory clinical study offering a simplified regimen medical abortion to women in Turkey. A total of 208 women from five sites were recruited from July 2000 through March 2001. All eligible consenting women were given 200 mg oral mifepristone at the c...

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Bibliographic Details
Published in:Contraception (Stoneham) 2004-11, Vol.70 (5), p.401-406
Main Authors: Akin, Ayse, Blum, Jennifer, Özalp, Sinan, Önderoğlu, Lütfü, Kırca, Üzeyir, Bilgili, Nihal, Koçoğlu, Gonca, Philip, Neena, Winikoff, Beverly
Format: Article
Language:English
Subjects:
Abortifacient Agents, Nonsteroidal - administration & dosage
Abortion, Induced - methods
Abortion, Induced - statistics & numerical data
Adult
Ambulatory Care Facilities
Decision Making
Female
Humans
Low resource countries
Male
Medical abortion
Mifepristone
Misoprostol - administration & dosage
Patient Satisfaction
Pregnancy
Treatment Failure
Treatment Outcome
Turkey
Turkey - epidemiology
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Summary:This article presents results from a small, introductory clinical study offering a simplified regimen medical abortion to women in Turkey. A total of 208 women from five sites were recruited from July 2000 through March 2001. All eligible consenting women were given 200 mg oral mifepristone at the clinic followed by 400   μg oral misoprostol 2 days later either at home or at the clinic. The overall success rate of 84.1% is lower than in previous studies of this regimen, and a surprisingly high proportion of women (9.1%) were diagnosed with incomplete abortion. In spite of the higher than expected failure rate, women expressed a high degree of satisfaction. Several challenges were faced during this study, providing valuable insights about ways to introduce medical abortion into new settings with the best chances for success.
ISSN:0010-7824
1879-0518
DOI:10.1016/j.contraception.2004.05.005