Agreement and disagreement between contrast-enhanced magnetic resonance imaging and nuclear imaging for assessment of myocardial viability

Purpose The purpose of this study was to compare contrast-enhanced MRI and nuclear imaging with 99m Tc-tetrofosmin and 18 F-fluorodeoxyglucose ( 18 F-FDG) single photon emission computed tomography (SPECT) for assessment of myocardial viability. Methods Included in the study were 60 patients with se...

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Bibliographic Details
Published in:European journal of nuclear medicine and molecular imaging 2009-04, Vol.36 (4), p.594-601
Main Authors: Roes, Stijntje D., Kaandorp, Theodorus A. M., Ajmone Marsan, Nina, Westenberg, Jos J. M., Dibbets-Schneider, Petra, Stokkel, Marcel P., Lamb, Hildo J., van der Wall, Ernst E., de Roos, Albert, Bax, Jeroen J.
Format: Article
Language:English
Subjects:
Aged
Cardiology
Cardiology - methods
Cardiovascular disease
Contrast Media - pharmacology
Female
Fluorodeoxyglucose F18 - pharmacology
Heart - diagnostic imaging
Humans
Imaging
Magnetic Resonance Imaging - methods
Male
Medical diagnosis
Medical imaging
Medical prognosis
Medicine
Medicine & Public Health
Middle Aged
Myocardium - pathology
NMR
Nuclear magnetic resonance
Nuclear Medicine
Oncology
Organophosphorus Compounds - chemistry
Organophosphorus Compounds - pharmacology
Organotechnetium Compounds - chemistry
Organotechnetium Compounds - pharmacology
Original Article
Orthopedics
Radiology
Radiopharmaceuticals - chemistry
Radiopharmaceuticals - pharmacology
Tomography, Emission-Computed, Single-Photon - methods
Ventricular Dysfunction, Left - diagnosis
Ventricular Dysfunction, Left - diagnostic imaging
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Summary:Purpose The purpose of this study was to compare contrast-enhanced MRI and nuclear imaging with 99m Tc-tetrofosmin and 18 F-fluorodeoxyglucose ( 18 F-FDG) single photon emission computed tomography (SPECT) for assessment of myocardial viability. Methods Included in the study were 60 patients with severe ischaemic left ventricular (LV) dysfunction who underwent contrast-enhanced MRI, 99m Tc-tetrofosmin and 18 F-FDG SPECT. Myocardial segments were assigned a wall motion score from 0 (normokinesia) to 4 (dyskinesia) and a scar score from 0 (no scar) to 4 (76–100% transmural extent). Furthermore, 99m Tc-tetrofosmin and 18 F-FDG segmental tracer uptake was categorized from 0 (tracer activity >75%) to 3 (tracer activity
ISSN:1619-7070
1619-7089
DOI:10.1007/s00259-008-1001-0