Aortic Remodeling in Type B Aortic Dissection: Effects of Endovascular Stent-Graft Repair and Medical Treatment on True and False Lumen Volumes

• Published in: Journal of endovascular therapy 2009-02, Vol.16 (1), p.28-38
• Main Authors: Huptas, Sebastian, Mehta, Rajendra H., KÜhl, Hilmar, Tsagakis, Konstantinos, Reinsch, Nico, Kahlert, Philipp, Jakob, Heinz G., Eggebrecht, Holger
• Format: Article
• Language: English
• Subjects: Adult; Aged; Aneurysm, Dissecting - diagnostic imaging; Aneurysm, Dissecting - drug therapy; Aneurysm, Dissecting - surgery; Antihypertensive Agents - therapeutic use; Aortic Aneurysm - diagnostic imaging; Aortic Aneurysm - drug therapy; Aortic Aneurysm - surgery; Aortography - methods; Blood clots; Blood pressure; Blood Vessel Prosthesis; Blood Vessel Prosthesis Implantation - instrumentation; Clinical trials; Dissection; Female; Follow-Up Studies; Humans; Imaging, Three-Dimensional; Male; Medical imaging; Medical treatment; Middle Aged; Patients; Retrospective Studies; Stents; Thrombosis; Time Factors; Tomography; Tomography, X-Ray Computed; Treatment Outcome; Veins & arteries; Volumetric analysis
• ISSN: 1526-6028; 1545-1550
• DOI: 10.1583/08-2497.1

Purpose: To analyze aortic remodeling processes in terms of true (TL) and false lumen (FL) volumes in patients with type B aortic dissection undergoing thoracic endovascular aortic repair (TEVAR) versus patients treated medically. Methods: Serial contrast-enhanced computed tomography (CT) scans of 27 type B dissection patients (24 men; mean age 60±13 years) who underwent TEVAR (n=17) or medical therapy only (n=10) were analyzed. TL and FL volumes over the entire descending aorta at baseline and at follow-up were quantified by 3-dimensional reconstruction. Results: Follow-up in the 27 patients was a mean 14±6 months. TEVAR resulted in a continued gain in total TL volume (132±56 mL at baseline, 164±51 mL early after TEVAR, and 220±68 mL at follow-up, p