Use of Gadolinium Contrast Adrenal Venography for the Assessment of Primary Aldosteronism in a Patient with Iodine Allergy

Primary aldosteronism is a relatively common cause of secondary hypertension. It is often important to diagnose this disease accurately, since appropriate surgical therapy may result in cure of the disease. Assessment of the laterality of adrenal hyperfunction is possible using adrenal venous sampli...

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Bibliographic Details
Published in:Endocrine Journal 2004, Vol.51(5), pp.487-492
Main Authors: SASAMURA, Hiroyuki, HASHIMOTO, Subaru, KURIBAYASHI, Sachio, UENO, Koichi, TAKASE, Atsushi, HAYASHI, Matsuhiko, SARUTA, Takao
Format: Article
Language:English
Subjects:
Adrenal Gland Neoplasms - diagnostic imaging
Adrenal Gland Neoplasms - pathology
Adrenal Glands - blood supply
Adrenal Glands - diagnostic imaging
Adrenal Glands - pathology
Adult
Contrast Media
Female
Gadolinium
Humans
Hyperaldosteronism - diagnostic imaging
Hypersensitivity
Iodine
Magnetic Resonance Imaging
Phlebography - methods
Primary aldosteronism
Tomography, X-Ray Computed
Venography
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Summary:Primary aldosteronism is a relatively common cause of secondary hypertension. It is often important to diagnose this disease accurately, since appropriate surgical therapy may result in cure of the disease. Assessment of the laterality of adrenal hyperfunction is possible using adrenal venous sampling of steroid hormones, but this procedure may not be feasible in patients with allergy to iodinated radiocontrast agents. In this paper, we report a patient with primary aldosteronism who was found to have bilateral adrenal tumors on CT. Because preoperative localization of the hyperfunctioning tumor was important, adrenal venous sampling and venography was performed by a highly-experienced radiologist using the MRI contrast agent gadolinium. After reviewing the data, the patient received a right adrenalectomy. This case report demonstrates that it was possible to perform adrenal venography using gadolinium in this patient, however the safety and efficacy should be re-assessed in individual cases.
ISSN:0918-8959
1348-4540
DOI:10.1507/endocrj.51.487