Aortic stenosis

Summary In developed countries, aortic stenosis is the most prevalent of all valvular heart diseases. A manifestation of ageing, the disorder is becoming more frequent as the average age of the population increases. Symptomatic severe disease is universally fatal if left untreated yet is consistent...

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Bibliographic Details
Published in:The Lancet (British edition) 2009-03, Vol.373 (9667), p.956-966
Main Authors: Carabello, Blase A, Prof, Paulus, Walter J, Prof
Format: Article
Language:English
Subjects:
Aging - pathology
Angioplasty, Balloon, Coronary
Aortic Valve Stenosis - etiology
Aortic Valve Stenosis - physiopathology
Aortic Valve Stenosis - therapy
Biological and medical sciences
Biomarkers
Calcinosis - complications
Cardiac Catheterization
Cardiac Output
Cardiology
Cardiology. Vascular system
Cardiovascular disease
Endocardial and cardiac valvular diseases
Female
General aspects
Heart
Heart failure
Heart Valve Prosthesis
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use
Industrialized nations
Internal Medicine
Male
Medical sciences
Mortality
Patients
Physical Examination
Rheumatic fever
Survival Analysis
Syncope - etiology
Vein & artery diseases
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Description
Summary:Summary In developed countries, aortic stenosis is the most prevalent of all valvular heart diseases. A manifestation of ageing, the disorder is becoming more frequent as the average age of the population increases. Symptomatic severe disease is universally fatal if left untreated yet is consistent with a typical lifespan when mechanical relief of the stenosis is provided in a timely fashion. Management of mild disease, severe asymptomatic disease, and far advanced disease, and the effect of new percutaneous treatments, provide both controversy and exciting promise to care of patients with aortic stenosis. We discuss these issues in this Review.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(09)60211-7