Mammalian phylogenomics comes of age

The relatively new field of phylogenomics is beginning to reveal the potential of genomic data for evolutionary studies. As the cost of whole genome sequencing falls, anticipation of complete genome sequences from divergent species, reflecting the major lineages of modern mammals, is no longer a dis...

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Bibliographic Details
Published in:Trends in genetics 2004-12, Vol.20 (12), p.631-639
Main Authors: Murphy, William J., Pevzner, Pavel A., O'Brien, Stephen J.
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Evolution, Molecular
Fundamental and applied biological sciences. Psychology
Genetics of eukaryotes. Biological and molecular evolution
Genome
Genome, Human
Genomics
Humans
Mammals - genetics
Models, Genetic
Molecular and cellular biology
Phylogeny
Synteny
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Summary:The relatively new field of phylogenomics is beginning to reveal the potential of genomic data for evolutionary studies. As the cost of whole genome sequencing falls, anticipation of complete genome sequences from divergent species, reflecting the major lineages of modern mammals, is no longer a distant dream. In this article, we describe how comparative genomic data from mammals is progressing to resolve long-standing phylogenetic controversies, to refine dogma on how chromosomes evolve and to guide annotation of human and other vertebrate genomes.
ISSN:0168-9525
DOI:10.1016/j.tig.2004.09.005