Physiologic changes in vascular birthmarks during early infancy: Mechanisms and clinical implications

Vascular birthmarks are the most common birthmarks encountered in newborns. Many dermatologists are unfamiliar with the normal physiologic changes that affect and alter their appearance during early infancy. In this article we discuss normal newborn hemodynamic/neurovascular physiology and the assoc...

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Published in:Journal of the American Academy of Dermatology 2009-04, Vol.60 (4), p.669-675
Main Authors: Cordoro, Kelly M., MD, Speetzen, Larisa S., MD, Koerper, Marion A., MD, Frieden, Ilona J., MD
Format: Article
Language:English
Subjects:
Biological and medical sciences
Dermatology
Hemangioma - pathology
Hemangioma - physiopathology
Humans
Infant, Newborn
Medical sciences
Skin - pathology
Skin - physiopathology
Skin Neoplasms - pathology
Skin Neoplasms - physiopathology
Skin Physiological Phenomena
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creator Cordoro, Kelly M., MD
Speetzen, Larisa S., MD
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Frieden, Ilona J., MD
description Vascular birthmarks are the most common birthmarks encountered in newborns. Many dermatologists are unfamiliar with the normal physiologic changes that affect and alter their appearance during early infancy. In this article we discuss normal newborn hemodynamic/neurovascular physiology and the associated clinical findings in neonatal skin. The physiologic anemia of infancy and its resultant effects on skin color and the appearance of vascular birthmarks are detailed. Finally, the pitfalls and obstacles to early diagnosis of vascular birthmarks and the subtle differences between them are reviewed, as are the challenges in assessing response to early pulsed dye laser treatment in the context of the changing vascular physiology.
doi_str_mv 10.1016/j.jaad.2008.11.020
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subjects Biological and medical sciences
Dermatology
Hemangioma - pathology
Hemangioma - physiopathology
Humans
Infant, Newborn
Medical sciences
Skin - pathology
Skin - physiopathology
Skin Neoplasms - pathology
Skin Neoplasms - physiopathology
Skin Physiological Phenomena
title Physiologic changes in vascular birthmarks during early infancy: Mechanisms and clinical implications
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