Cerebral regional oxygen fluctuations and decline during clinically silent focal electroencephalographic seizures in a neonate

We describe a neonate with tuberous sclerosis complex and right frontal cortical dysplasia who underwent simultaneous near-infrared spectroscopy and electroencephalography (EEG) during repetitive clinically silent right frontal EEG seizures. The seizures produced a progressive decline in regional ox...

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Bibliographic Details
Published in:Journal of child neurology 2004-07, Vol.19 (7), p.539-540
Main Authors: Shuhaiber, Hans, Bolton, Scott, Alfonso, Israel, Dunoyer, Catalina, Yaylali, Ilker
Format: Article
Language:English
Subjects:
Brain - metabolism
Electroencephalography
False Negative Reactions
Humans
Infant, Newborn
Infant, Newborn, Diseases
Male
Oxygen - analysis
Seizures - etiology
Seizures - pathology
Tuberous Sclerosis - complications
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Summary:We describe a neonate with tuberous sclerosis complex and right frontal cortical dysplasia who underwent simultaneous near-infrared spectroscopy and electroencephalography (EEG) during repetitive clinically silent right frontal EEG seizures. The seizures produced a progressive decline in regional oxygen saturation index and wider regional oxygen saturation index fluctuations in the right hemisphere than in the left hemisphere. We conclude that recurrent clinically silent focal EEG seizures in this neonate were associated with lateralizing near-infrared spectroscopy changes suggestive of relative cerebral hypoxia.
ISSN:0883-0738