Acral, Pure Cutaneous, Self-Healing, Late-Onset, Cellulitis-Like Langerhans Cell Histiocytosis

Background: An unusual and not yet reported clinical presentation of pure cutaneous Langerhans cell histiocytosis (LCH) that was a diagnostic dilemma. Objective: To bring to light the newer presentation of this disease. Method: The case was managed on clinical grounds initially as cellulitis. Howeve...

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Bibliographic Details
Published in:Journal of cutaneous medicine and surgery 2009-01, Vol.13 (1), p.43-47
Main Authors: Sharma, Prafulla Kumar, Sabhnani, Sunil, Bhardwaj, Minakshi, Kar, Hemanta Kumar
Format: Article
Language:English
Subjects:
Adult
Age of Onset
Biological and medical sciences
Biopsy
Cellulitis - epidemiology
Comorbidity
Dermatology
Erythema - epidemiology
Female
Hematologic and hematopoietic diseases
Histiocytosis, Langerhans-Cell - diagnosis
Histiocytosis, Langerhans-Cell - epidemiology
Histiocytosis, Langerhans-Cell - pathology
Humans
Immunotherapy
Infections
Lymphangitis - epidemiology
Medical sciences
Other diseases. Hematologic involvement in other diseases
Skin diseases
Skin Diseases - diagnosis
Skin Diseases - pathology
Skin involvement in other diseases. Miscellaneous. General aspects
Studies
Citations: Items that this one cites
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Description
Summary:Background: An unusual and not yet reported clinical presentation of pure cutaneous Langerhans cell histiocytosis (LCH) that was a diagnostic dilemma. Objective: To bring to light the newer presentation of this disease. Method: The case was managed on clinical grounds initially as cellulitis. However, after the investigations and confirmation of the diagnosis, she was managed symptomatically. Results: Pure cutaneous LCH may manifest in early adulthood with features of cellulitis, erythematous edematous vesicular plaques, and nodules distributed in the flexural acral areas. Conclusion: Pure cutaneous LCH may have an acute late onset with unusual morphology as cellulitis, inverse acral distribution, and self-healing.
ISSN:1203-4754
1615-7109
DOI:10.2310/7750.2008.07078