A laboratory assessment of coronal bacterial leakage in root canals filled with new and conventional sealers

Aim  To evaluate the resistance to ex vivo bacterial leakage over a 40‐day period of root canal fillings with five new root canal sealers: RC Sealer, Epiphany, EndoREZ, GuttaFlow and Acroseal, compared with Apexit, AH Plus and RoekoSeal. Methodology  One hundred and forty‐four single rooted human te...

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Published in:International endodontic journal 2009-04, Vol.42 (4), p.303-312
Main Authors: Eldeniz, A. U., Ørstavik, D.
Format: Article
Language:English
Subjects:
Bacteria
bacterial leakage
Dental Leakage - prevention & control
Dentistry
Humans
Kaplan-Meier Estimate
methacrylate
Nephelometry and Turbidimetry
new sealers
polycaprolactone
Root Canal Filling Materials - pharmacology
Root Canal Filling Materials - therapeutic use
silicone
Streptococcus mutans
Streptococcus mutans - drug effects
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container_title International endodontic journal
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creator Eldeniz, A. U.
Ørstavik, D.
description Aim  To evaluate the resistance to ex vivo bacterial leakage over a 40‐day period of root canal fillings with five new root canal sealers: RC Sealer, Epiphany, EndoREZ, GuttaFlow and Acroseal, compared with Apexit, AH Plus and RoekoSeal. Methodology  One hundred and forty‐four single rooted human teeth were divided randomly into eight test (n = 15) and two control groups (n = 12). The root canals were filled using a single cone technique with gutta‐percha except in the Epiphany and EndoREZ groups. These were filled with Resilon and resin‐coated gutta‐percha, respectively. The gutta‐percha surface of the GuttaFlow group was coated with an experimental primer prior to filling. Positive controls were filled with gutta‐percha without sealer and tested with bacteria, whereas negative controls were sealed with wax to test the seal between the chambers. Filled roots were incorporated in a split chamber model system using Streptococcus mutans as a microbial marker. Leakage was assessed for turbidity of the broth in the lower chamber every day for 40 days. Survival analysis was performed using the Kaplan–Meier product limit method and event times were compared using the Log‐rank test (α = 0.05). Results  Epiphany, GuttaFlow with test primer and Apexit prevented leakage significantly better than AH Plus, RC Sealer, RoekoSeal, EndoREZ and Acroseal (P 
doi_str_mv 10.1111/j.1365-2591.2008.01509.x
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U. ; Ørstavik, D.</creator><creatorcontrib>Eldeniz, A. U. ; Ørstavik, D.</creatorcontrib><description>Aim  To evaluate the resistance to ex vivo bacterial leakage over a 40‐day period of root canal fillings with five new root canal sealers: RC Sealer, Epiphany, EndoREZ, GuttaFlow and Acroseal, compared with Apexit, AH Plus and RoekoSeal. Methodology  One hundred and forty‐four single rooted human teeth were divided randomly into eight test (n = 15) and two control groups (n = 12). The root canals were filled using a single cone technique with gutta‐percha except in the Epiphany and EndoREZ groups. These were filled with Resilon and resin‐coated gutta‐percha, respectively. The gutta‐percha surface of the GuttaFlow group was coated with an experimental primer prior to filling. Positive controls were filled with gutta‐percha without sealer and tested with bacteria, whereas negative controls were sealed with wax to test the seal between the chambers. Filled roots were incorporated in a split chamber model system using Streptococcus mutans as a microbial marker. Leakage was assessed for turbidity of the broth in the lower chamber every day for 40 days. Survival analysis was performed using the Kaplan–Meier product limit method and event times were compared using the Log‐rank test (α = 0.05). Results  Epiphany, GuttaFlow with test primer and Apexit prevented leakage significantly better than AH Plus, RC Sealer, RoekoSeal, EndoREZ and Acroseal (P &lt; 0.05). None of the specimens in the AH Plus, RC Sealer, RoekoSeal and EndoREZ groups resisted bacterial penetration for 40 days. Conclusion  The new sealers, Epiphany and GuttaFlow with primer, along with Apexit, showed better resistance to bacterial penetration than the other new or traditional sealers tested.</description><identifier>ISSN: 0143-2885</identifier><identifier>EISSN: 1365-2591</identifier><identifier>DOI: 10.1111/j.1365-2591.2008.01509.x</identifier><identifier>PMID: 19220520</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Bacteria ; bacterial leakage ; Dental Leakage - prevention &amp; control ; Dentistry ; Humans ; Kaplan-Meier Estimate ; methacrylate ; Nephelometry and Turbidimetry ; new sealers ; polycaprolactone ; Root Canal Filling Materials - pharmacology ; Root Canal Filling Materials - therapeutic use ; silicone ; Streptococcus mutans ; Streptococcus mutans - drug effects</subject><ispartof>International endodontic journal, 2009-04, Vol.42 (4), p.303-312</ispartof><rights>2009 International Endodontic Journal</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4369-92a6fe08fda7db3f50caa9153f2feb486d67c8b24c95d929a62fcd2a6e195e233</citedby><cites>FETCH-LOGICAL-c4369-92a6fe08fda7db3f50caa9153f2feb486d67c8b24c95d929a62fcd2a6e195e233</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19220520$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Eldeniz, A. U.</creatorcontrib><creatorcontrib>Ørstavik, D.</creatorcontrib><title>A laboratory assessment of coronal bacterial leakage in root canals filled with new and conventional sealers</title><title>International endodontic journal</title><addtitle>Int Endod J</addtitle><description>Aim  To evaluate the resistance to ex vivo bacterial leakage over a 40‐day period of root canal fillings with five new root canal sealers: RC Sealer, Epiphany, EndoREZ, GuttaFlow and Acroseal, compared with Apexit, AH Plus and RoekoSeal. Methodology  One hundred and forty‐four single rooted human teeth were divided randomly into eight test (n = 15) and two control groups (n = 12). The root canals were filled using a single cone technique with gutta‐percha except in the Epiphany and EndoREZ groups. These were filled with Resilon and resin‐coated gutta‐percha, respectively. The gutta‐percha surface of the GuttaFlow group was coated with an experimental primer prior to filling. Positive controls were filled with gutta‐percha without sealer and tested with bacteria, whereas negative controls were sealed with wax to test the seal between the chambers. Filled roots were incorporated in a split chamber model system using Streptococcus mutans as a microbial marker. Leakage was assessed for turbidity of the broth in the lower chamber every day for 40 days. Survival analysis was performed using the Kaplan–Meier product limit method and event times were compared using the Log‐rank test (α = 0.05). Results  Epiphany, GuttaFlow with test primer and Apexit prevented leakage significantly better than AH Plus, RC Sealer, RoekoSeal, EndoREZ and Acroseal (P &lt; 0.05). None of the specimens in the AH Plus, RC Sealer, RoekoSeal and EndoREZ groups resisted bacterial penetration for 40 days. Conclusion  The new sealers, Epiphany and GuttaFlow with primer, along with Apexit, showed better resistance to bacterial penetration than the other new or traditional sealers tested.</description><subject>Bacteria</subject><subject>bacterial leakage</subject><subject>Dental Leakage - prevention &amp; control</subject><subject>Dentistry</subject><subject>Humans</subject><subject>Kaplan-Meier Estimate</subject><subject>methacrylate</subject><subject>Nephelometry and Turbidimetry</subject><subject>new sealers</subject><subject>polycaprolactone</subject><subject>Root Canal Filling Materials - pharmacology</subject><subject>Root Canal Filling Materials - therapeutic use</subject><subject>silicone</subject><subject>Streptococcus mutans</subject><subject>Streptococcus mutans - drug effects</subject><issn>0143-2885</issn><issn>1365-2591</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><recordid>eNqNkU9v1DAQxS0EokvhKyCfuCX4T5zYBw5VaUvLqlyK4GY5zhi89cbFzrK73x6nuypH8MUjzfu90cxDCFNS0_Ler2rKW1ExoWjNCJE1oYKoevcMLZ4az9GC0IZXTEpxgl7lvCKECMLpS3RCFWNEMLJA4QwH08dkppj22OQMOa9hnHB02MYURxNwb-wEyZcqgLk3PwD7EacYJ2xN6WfsfAgw4K2ffuIRttiMQ4HH38XHPzpkMAFSfo1euKKHN8f_FH29vLg7_1Qtv1xdn58tK9vwVlWKmdYBkW4w3dBzJ4g1RlHBHXPQN7Id2s7KnjVWiUExZVrm7FAgoEoA4_wUvTv4PqT4awN50mufLYRgRoibrNuuLN_I7p_CcqRGKt4UoTwIbYo5J3D6Ifm1SXtNiZ4j0Ss9X17Pl9dzJPoxEr0r6NvjjE2_huEveMygCD4cBFsfYP_fxvr64mauCl8deJ8n2D3xJt2XRXkn9LfbK93cLD9-vv0u9B3_A7l-qxM</recordid><startdate>200904</startdate><enddate>200904</enddate><creator>Eldeniz, A. 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U. ; Ørstavik, D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4369-92a6fe08fda7db3f50caa9153f2feb486d67c8b24c95d929a62fcd2a6e195e233</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Bacteria</topic><topic>bacterial leakage</topic><topic>Dental Leakage - prevention &amp; control</topic><topic>Dentistry</topic><topic>Humans</topic><topic>Kaplan-Meier Estimate</topic><topic>methacrylate</topic><topic>Nephelometry and Turbidimetry</topic><topic>new sealers</topic><topic>polycaprolactone</topic><topic>Root Canal Filling Materials - pharmacology</topic><topic>Root Canal Filling Materials - therapeutic use</topic><topic>silicone</topic><topic>Streptococcus mutans</topic><topic>Streptococcus mutans - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Eldeniz, A. U.</creatorcontrib><creatorcontrib>Ørstavik, D.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>International endodontic journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Eldeniz, A. U.</au><au>Ørstavik, D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A laboratory assessment of coronal bacterial leakage in root canals filled with new and conventional sealers</atitle><jtitle>International endodontic journal</jtitle><addtitle>Int Endod J</addtitle><date>2009-04</date><risdate>2009</risdate><volume>42</volume><issue>4</issue><spage>303</spage><epage>312</epage><pages>303-312</pages><issn>0143-2885</issn><eissn>1365-2591</eissn><abstract>Aim  To evaluate the resistance to ex vivo bacterial leakage over a 40‐day period of root canal fillings with five new root canal sealers: RC Sealer, Epiphany, EndoREZ, GuttaFlow and Acroseal, compared with Apexit, AH Plus and RoekoSeal. Methodology  One hundred and forty‐four single rooted human teeth were divided randomly into eight test (n = 15) and two control groups (n = 12). The root canals were filled using a single cone technique with gutta‐percha except in the Epiphany and EndoREZ groups. These were filled with Resilon and resin‐coated gutta‐percha, respectively. The gutta‐percha surface of the GuttaFlow group was coated with an experimental primer prior to filling. Positive controls were filled with gutta‐percha without sealer and tested with bacteria, whereas negative controls were sealed with wax to test the seal between the chambers. Filled roots were incorporated in a split chamber model system using Streptococcus mutans as a microbial marker. Leakage was assessed for turbidity of the broth in the lower chamber every day for 40 days. Survival analysis was performed using the Kaplan–Meier product limit method and event times were compared using the Log‐rank test (α = 0.05). Results  Epiphany, GuttaFlow with test primer and Apexit prevented leakage significantly better than AH Plus, RC Sealer, RoekoSeal, EndoREZ and Acroseal (P &lt; 0.05). None of the specimens in the AH Plus, RC Sealer, RoekoSeal and EndoREZ groups resisted bacterial penetration for 40 days. Conclusion  The new sealers, Epiphany and GuttaFlow with primer, along with Apexit, showed better resistance to bacterial penetration than the other new or traditional sealers tested.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>19220520</pmid><doi>10.1111/j.1365-2591.2008.01509.x</doi><tpages>10</tpages></addata></record>
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source Wiley-Blackwell Read & Publish Collection
subjects Bacteria
bacterial leakage
Dental Leakage - prevention & control
Dentistry
Humans
Kaplan-Meier Estimate
methacrylate
Nephelometry and Turbidimetry
new sealers
polycaprolactone
Root Canal Filling Materials - pharmacology
Root Canal Filling Materials - therapeutic use
silicone
Streptococcus mutans
Streptococcus mutans - drug effects
title A laboratory assessment of coronal bacterial leakage in root canals filled with new and conventional sealers
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