Seroepidemiology of neutralizing antibodies to Japanese encephalitis virus in Singapore: continued transmission despite abolishment of pig farming?

Japanese encephalitis virus (JEV) transmission in Singapore appeared to have ceased after pig farming in Singapore was phased out from the early 1980s. However, the recent detection of neutralizing antibodies to JEV in a population of wild boars in an offshore island, as well as the notification of...

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Bibliographic Details
Published in:Acta tropica 2004-11, Vol.92 (3), p.187-191
Main Authors: Ting, Shirley Hui Ling, Tan, Hwee Cheng, Wong, Wai Kwan, Ng, Mah Lee, Chan, Soh Ha, Ooi, Eng Eong
Format: Article
Language:English
Subjects:
Adolescent
Agriculture - legislation & jurisprudence
Animals
Animals, Domestic - immunology
Animals, Wild - immunology
Antibodies, Viral - blood
Biological and medical sciences
Child
Child, Preschool
Encephalitis Virus, Japanese - immunology
Encephalitis, Japanese - transmission
Encephalitis, Japanese - veterinary
General aspects
Humans
Infant
Japanese encephalitis virus
Japanese encephalitis virus (JEV)
Medical sciences
Neutralizing antibodies
Seroepidemiologic Studies
Seroprevalence
Singapore - epidemiology
Swine
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Summary:Japanese encephalitis virus (JEV) transmission in Singapore appeared to have ceased after pig farming in Singapore was phased out from the early 1980s. However, the recent detection of neutralizing antibodies to JEV in a population of wild boars in an offshore island, as well as the notification of two human cases of JE in Singapore in 2001, prompted us to reconsider the presence and hence the public health threat of JEV in Singapore. We report here a serological study of animals, birds and humans for neutralizing antibodies to JEV. The results indicate that JEV may still be actively transmitted in the peripheral part of the Singapore island and that regular serological surveys of farm animals and birds, such as chickens, may be useful to further elucidate the activity of JEV in Singapore.
ISSN:0001-706X
1873-6254
DOI:10.1016/j.actatropica.2004.04.010