Molecular epidemiology of group B streptococcal infections

Streptococcus agalactiae (GBS) is a causative agent of sepsis and meningitis in newborns and diseases in pregnant women and nonpregnant adults. Various approaches, including both nongenetic and genetic techniques, are currently used for the study of epidemiology of GBS infections. In the present pap...

Full description

Saved in:
Bibliographic Details
Published in:Folia microbiologica 2004-01, Vol.49 (4), p.387-397
Main Authors: Tkáčiková, L, Mikula, I, Dmitriev, A
Format: Article
Language:English
Subjects:
adults
Animals
clones
genetic techniques and protocols
Humans
meningitis
molecular epidemiology
neonates
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length
pregnant women
Random Amplified Polymorphic DNA Technique
Ribotyping
sepsis (infection)
Streptococcal Infections - diagnosis
Streptococcal Infections - epidemiology
Streptococcus agalactiae
Streptococcus agalactiae - genetics
Virulence
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Streptococcus agalactiae (GBS) is a causative agent of sepsis and meningitis in newborns and diseases in pregnant women and nonpregnant adults. Various approaches, including both nongenetic and genetic techniques, are currently used for the study of epidemiology of GBS infections. In the present paper the different methods of molecular epidemiology of GBS infections are reviewed, and several novel approaches are introduced. The advantages and disadvantages of molecular methods are discussed and compared with traditional serotyping technique. The possible use of the molecular approaches for identification of different genetic lineages in GBS as well as for identification and control of the epidemiologically actual clones is discussed.
ISSN:0015-5632
1874-9356
DOI:10.1007/BF03354665