Von Hippel-Lindau disease in pregnancy: A brief review

Abstract The hormonal and hemodynamic effects of pregnancy accelerate the growth of hemangioblastomas in Von Hippel-Lindau syndrome (VHL), leading to increased symptoms and risk to both the mother and fetus. A review of the literature on the treatment of VHL in pregnancy would suggest surgical inter...

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Bibliographic Details
Published in:Journal of clinical neuroscience 2009-05, Vol.16 (5), p.611-613
Main Authors: Hayden, Melanie G, Gephart, Rosanne, Kalanithi, Paul, Chou, Dean
Format: Article
Language:English
Subjects:
Cervical spine
Female
Hemangioblastoma
Hemangioblastoma - complications
Hemangioblastoma - pathology
Humans
Magnetic Resonance Imaging
Neurology
Pregnancy
Pregnant Women
Spinal Neoplasms - complications
Spinal Neoplasms - pathology
Von Hippel-Lindau
von Hippel-Lindau Disease - complications
von Hippel-Lindau Disease - etiology
von Hippel-Lindau Disease - pathology
von Hippel-Lindau Disease - therapy
Young Adult
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Summary:Abstract The hormonal and hemodynamic effects of pregnancy accelerate the growth of hemangioblastomas in Von Hippel-Lindau syndrome (VHL), leading to increased symptoms and risk to both the mother and fetus. A review of the literature on the treatment of VHL in pregnancy would suggest surgical intervention should be considered with worsening clinical status. Introducing this review is a description of our patient with VHL, who uniquely presented in pregnancy with a cervical hemangioblastoma.
ISSN:0967-5868
1532-2653
DOI:10.1016/j.jocn.2008.05.032