The no‐reflow phenomenon in coronary arteries

No reflow occurs when there is inadequate myocardial perfusion of a given segment of the coronary circulation without evidence of epicardial vessel obstruction. It is a rare but clinically significant condition associated with myocardial infarction and coronary interventions. Diagnosis is usually ba...

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Bibliographic Details
Published in:Journal of thrombosis and haemostasis 2004-11, Vol.2 (11), p.1903-1907
Main Authors: Kelly, R.V., Cohen, M.G., Runge, M.S., Stouffer, G. A.
Format: Article
Language:English
Subjects:
Coronary Circulation
Coronary Vessels - physiopathology
Disease Management
Humans
Myocardial Ischemia - etiology
Thromboembolism - complications
Vascular Diseases - diagnosis
Vascular Diseases - etiology
Vascular Diseases - therapy
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Summary:No reflow occurs when there is inadequate myocardial perfusion of a given segment of the coronary circulation without evidence of epicardial vessel obstruction. It is a rare but clinically significant condition associated with myocardial infarction and coronary interventions. Diagnosis is usually based on clinical signs of myocardial ischemia (symptoms and/or ECG changes) combined with coronary angiography. Management can be difficult and primarily consists of intracoronary administration of vasodilators. One interesting etiology is thromboembolism and this has become the focus for new potential treatments, including distal embolic protection devices.
ISSN:1538-7933
1538-7836
1538-7836
DOI:10.1111/j.1538-7836.2004.00898.x