Ofloxacin is contraindicated in case of G6PD deficiency: is it evidenced based?

G6PD deficiency is very frequent with almost 400 millions of patients worldwide in Asia, Africa and Mediterranean. G6PD deficiency is involved in mild or severe haemolysis and the precipitating factor is usually a drug. More than 100 drugs have been implicated and fluoroquinolones are one of the mor...

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Bibliographic Details
Published in:La revue de medecine interne 2009-04, Vol.30 (4), p.355-357
Main Authors: Carmoi, T, Bordier, L, Bonnefoy, S, Callot, D, Lecoules, S, Algayres, J-P
Format: Article
Language:fre
Subjects:
Contraindications
Diabetes Complications - drug therapy
Diabetes Complications - microbiology
Escherichia coli Infections - drug therapy
Female
Glucosephosphate Dehydrogenase Deficiency - complications
Humans
Insulin - therapeutic use
Middle Aged
Ofloxacin - therapeutic use
Urinary Tract Infections - drug therapy
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Summary:G6PD deficiency is very frequent with almost 400 millions of patients worldwide in Asia, Africa and Mediterranean. G6PD deficiency is involved in mild or severe haemolysis and the precipitating factor is usually a drug. More than 100 drugs have been implicated and fluoroquinolones are one of the more classic. However, the literature review shows that only a few observations have been clearly documented.
ISSN:0248-8663
DOI:10.1016/j.revmed.2008.07.007