Survey of the use of organic nitrates for the treatment of chronic congestive heart failure in the united states

A survey of members of the Heart Failure Society of America revealed that despite their lack of approval by the United States Food and Drug Administration, nitrates are widely used in patients with chronic congestive heart failure (CHF). Most members reported using nitrates in patients with ischemic...

Full description

Saved in:
Bibliographic Details
Published in:The American journal of cardiology 2004-12, Vol.94 (11), p.1465-1468
Main Authors: Bitar, Fahed, Akhter, Mohammed W., Khan, Salman, Singh, Harpreet, Elkayam, Uri
Format: Article
Language:English
Subjects:
Biological and medical sciences
Cardiology. Vascular system
Chronic Disease
Exercise Tolerance
Health Care Surveys
Heart
Heart failure
Heart Failure - drug therapy
Heart failure, cardiogenic pulmonary edema, cardiac enlargement
Hemodynamics
Humans
Medical sciences
Nitrates
Nitrates - therapeutic use
Practice Patterns, Physicians' - statistics & numerical data
United States
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A survey of members of the Heart Failure Society of America revealed that despite their lack of approval by the United States Food and Drug Administration, nitrates are widely used in patients with chronic congestive heart failure (CHF). Most members reported using nitrates in patients with ischemic (90%) and nonischemic (81%) causes of chronic CHF, especially those with symptomatic CHF (43% reported using nitrates in >50% of their patients with ischemic and 25% with nonischemic causes). Ninety-six percent reported using nitrates to reduce symptoms, 74% for hemodynamic improvement, 65% for better exercise tolerance, and only 14% for left ventricular reversed remodeling. Nitrates were always combined with hydralazine in 25% of patients and occasionally combined with hydralazine in 67%.
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2004.07.155