Automated measurement of lymph nodes: a phantom study

The purpose of this study was to assess the accuracy of automated nodal quantification in a phantom. MDCT of a phantom with 17 synthetic lymph nodes of different sizes (diameter 6.0–30.0 mm) was performed at varying tube currents, reconstruction kernels and slice thicknesses. RECIST diameter and vol...

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Bibliographic Details
Published in:European radiology 2009-05, Vol.19 (5), p.1079-1086
Main Authors: Keil, Sebastian, Plumhans, Cedric, Behrendt, Florian F., Stanzel, Sven, Suehling, Michael, Mühlenbruch, Georg, Mahnken, Andreas H., Günther, Rolf W., Das, Marco
Format: Article
Language:English
Subjects:
Abdomen
Accuracy
Algorithms
Automation
Computers
Diagnostic Radiology
Humans
Image Processing, Computer-Assisted
Imaging
Internal Medicine
Interventional Radiology
Lymph Nodes - diagnostic imaging
Lymph Nodes - pathology
Lymphatic system
Lymphoma
Magnetic resonance imaging
Measurement techniques
Medicine
Medicine & Public Health
Metastasis
Neoplasm Metastasis
Neuroradiology
Oncology
Pattern Recognition, Automated
Phantoms, Imaging
Radiographic Image Interpretation, Computer-Assisted - methods
Radiology
Reproducibility of Results
Software
Tomography
Tumors
Ultrasound
User-Computer Interface
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Summary:The purpose of this study was to assess the accuracy of automated nodal quantification in a phantom. MDCT of a phantom with 17 synthetic lymph nodes of different sizes (diameter 6.0–30.0 mm) was performed at varying tube currents, reconstruction kernels and slice thicknesses. RECIST diameter and volume were measured using an automated software tool. Results were compared with the reference diameter and volume by calculating the absolute percentage error (APE). Degree of agreement between software and reference measurements was evaluated by computing corresponding concordance correlation coefficients (CCC). Under varying tube currents the mean APE (CCC) varied between 5.18% and 10.12% (0.95–0.99) for RECIST diameter and between 7.22% and 16.21% (0.94–1.00) for the volume. At different reconstruction kernels the mean APE values ranged between 7.20% and 7.55% (0.99) (RECIST) and between 8.96% and 14.42% (1.00) (volume). With different slice thicknesses the mean APE values differed from 5.81% to 9.20% (0.97–0.99) (RECIST) and from 8.16% to 22.66% (0.99–1.00) (volume). Regarding RECIST criteria and volume, automated evaluation of lymph nodes in a phantom demonstrated a high accuracy under varying MDCT parameters.
ISSN:0938-7994
1432-1084
DOI:10.1007/s00330-008-1254-9