Urinary iodine in patients with auto-immune thyroid disorders in Santo André, SP, is comparable to normal controls and has been steady for the last 10 years

• Published in: Arquivos brasileiros de endocrinologia e metabologia 2009-02, Vol.53 (1), p.55-63
• Main Authors: Marino, Maria Angela Zaccarelli, Martins, Lourdes Conceição, Esteves, Roberto Z, Kasamatsu, Teresa S, Maciel, Rui M B
• Format: Article
• Language: Portuguese
• Subjects: Adolescent; Adult; Aged; Biomarkers - urine; Brazil; Case-Control Studies; Child; Child, Preschool; Diet - adverse effects; Female; Humans; Iodine - administration & dosage; Iodine - urine; Male; Middle Aged; Thyroid Gland - diagnostic imaging; Thyroiditis, Autoimmune - diagnosis; Thyroiditis, Autoimmune - etiology; Thyroiditis, Autoimmune - urine; Time Factors; Ultrasonography; Young Adult
• ISSN: 1677-9487
• DOI: 10.1590/s0004-27302009000100009

Evaluate whether the increase of iodine in the diet would be the triggering factor for auto-immune thyropathies in the city of Santo André, SP. Urinary iodine was determined in samples isolated from 58 patients, divided in 4 Groups, and in 13 normal individuals (controls). Urinary Iodine: Group 1--hyperthyroidism = 203.5+/-152.71 microg/ L(mean+/-sd); Group 2--hypothyroidism = 258.31+/-148,2 microg/L; Group 3--chronic auto-immune thyroiditis = 244.29+/-191.6 microg/L; Group 4--(Amiodarone) = 1157.5+/-261.8 microg/L; Group 5--Controls = 262.31+/-146.2 microg/L. On comparing the means of urinary iodine among the groups, the means for groups 1, 2, 3, and 5 did not present significant differences (p>0.05), and all differed from group 4 (p