Prognostic Value of Exercise Echocardiography in Patients With Left Bundle Branch Block

• Published in: JACC. Cardiovascular imaging 2009-03, Vol.2 (3), p.251-259
• Main Authors: Bouzas-Mosquera, Alberto, MD, Peteiro, Jesús, MD, PhD, Álvarez-García, Nemesio, MD, Broullón, Francisco J., MS, García-Bueno, Lourdes, MD, Ferro, Luis, MD, Pérez, Ruth, MD, Bouzas, Beatriz, MD, Fábregas, Ramón, MD, Castro-Beiras, Alfonso, MD, PhD
• Format: Article
• Language: English
• Subjects: Aged; Bundle-Branch Block - complications; Bundle-Branch Block - diagnostic imaging; Bundle-Branch Block - mortality; Bundle-Branch Block - physiopathology; Cardiovascular; Cardiovascular Diseases - diagnostic imaging; Cardiovascular Diseases - etiology; Cardiovascular Diseases - mortality; Cardiovascular Diseases - physiopathology; Coronary Artery Disease - complications; Coronary Artery Disease - diagnostic imaging; Coronary Artery Disease - mortality; Coronary Artery Disease - physiopathology; Databases as Topic; Echocardiography, Stress; Exercise Test; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Contraction; Myocardial Infarction - diagnostic imaging; Myocardial Infarction - etiology; Myocardial Infarction - physiopathology; Myocardial Ischemia - diagnostic imaging; Myocardial Ischemia - etiology; Myocardial Ischemia - physiopathology; Observer Variation; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Reproducibility of Results; Risk Assessment; Risk Factors; Time Factors
• ISSN: 1936-878X; 1876-7591
• DOI: 10.1016/j.jcmg.2008.11.014

Prognostic Value of Exercise Echocardiography in Patients With Left Bundle Branch Block Alberto Bouzas-Mosquera, Jesús Peteiro, Nemesio Álvarez-García, Francisco J. Broullón, Lourdes García-Bueno, Luis Ferro, Ruth Pérez, Beatriz Bouzas, Ramón Fábregas, Alfonso Castro-Beiras Pharmacologic stress echocardiography has previously been shown to predict outcome in left bundle branch block. This study of more than 600 patients, followed for 5 years, brings several new perspectives. First, exercise echocardiography also is shown to be effective for risk stratification, with change in wall motion score index being an independent predictor of total mortality and major cardiac events. Second, the results of exercise echocardiography are shown to provide incremental information to clinical, resting echocardiographic, and treadmill exercise data for predicting total mortality and major cardiac events.