Waist circumference reduction after insulin detemir therapy in type 2 diabetes patients previously treated with NPH

Abstract We studied the weight-sparing effect and treatment satisfaction when switching from NPH to insulin detemir in type 2 diabetes. Mean HbA1c ( P < 0.05) and waist circumference ( P < 0.05) were reduced while treatment satisfaction improved ( P < 0.03). No weight gain was observed. Det...

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Bibliographic Details
Published in:Diabetes research and clinical practice 2009-05, Vol.84 (2), p.e18-e20
Main Authors: Mandosi, E, Fallarino, M, Rossetti, M, Gatti, A, Morano, S
Format: Article
Language:English
Subjects:
Aged
Blood Glucose - drug effects
Blood Glucose - metabolism
Body Mass Index
Diabetes Mellitus, Type 2 - drug therapy
Endocrinology & Metabolism
Female
Glycated Hemoglobin A - drug effects
Glycated Hemoglobin A - metabolism
Humans
Hypoglycemic Agents - therapeutic use
Insulin - analogs & derivatives
Insulin - therapeutic use
Insulin Detemir
Insulin therapy
Insulin, Isophane - therapeutic use
Insulin, Long-Acting
Male
Middle Aged
NPH insulin
Patient Satisfaction
Type 2 diabetes
Waist Circumference - drug effects
Waist Circumference - physiology
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Summary:Abstract We studied the weight-sparing effect and treatment satisfaction when switching from NPH to insulin detemir in type 2 diabetes. Mean HbA1c ( P < 0.05) and waist circumference ( P < 0.05) were reduced while treatment satisfaction improved ( P < 0.03). No weight gain was observed. Detemir improves glycemic control, treatment satisfaction, and may provide additional weight-sparing benefits.
ISSN:0168-8227
1872-8227
DOI:10.1016/j.diabres.2009.02.006