Low Levels of Antiretroviral-Resistant HIV Infection in a Routine Clinic in Cameroon that Uses the World Health Organization (WHO) Public Health Approach to Monitor Antiretroviral Treatment and Adequacy with the WHO Recommendation for Second-Line Treatment

A cross-sectional study, performed at a routine human immunodeficiency virus (HIV)/AIDS clinic in Cameroon that uses the World Health Organization public health approach, showed low rates of virological failure and drug resistance at 12 and 24 months after initiation of antiretroviral therapy. Impor...

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Bibliographic Details
Published in:Clinical infectious diseases 2009-05, Vol.48 (9), p.1318-1322
Main Authors: Kouanfack, Charles, Montavon, Celine, Laurent, Christian, Aghokeng, Avelin, Kenfack, Alain, Bourgeois, Anke, Koulla-Shiro, Sinata, Mpoudi-Ngole, Eitel, Peeters, Martine, Delaporte, Eric
Format: Article
Language:English
Subjects:
Adult
Anti-HIV Agents - pharmacology
Anti-HIV Agents - therapeutic use
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antiretrovirals
Antiviral agents
Arts
Biological and medical sciences
Cameroon
Cross-Sectional Studies
Drug resistance
Drug Resistance, Viral
Female
Genetic mutation
Guideline Adherence
HIV
HIV - drug effects
HIV - isolation & purification
HIV 1
HIV infections
HIV Infections - drug therapy
HIV Infections - virology
HIV/AIDS
Human immunodeficiency virus
Human viral diseases
Humans
Immunodeficiencies
Immunodeficiencies. Immunoglobulinopathies
Immunopathology
Infectious diseases
Male
Medical sciences
Middle Aged
Pharmacology. Drug treatments
Public health
Treatment Outcome
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
Viral load
Virology
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Description
Summary:A cross-sectional study, performed at a routine human immunodeficiency virus (HIV)/AIDS clinic in Cameroon that uses the World Health Organization public health approach, showed low rates of virological failure and drug resistance at 12 and 24 months after initiation of antiretroviral therapy. Importantly, the cross-sectional study also showed that the World Health Organization recommendation for second-line treatment would be effective in almost all patients with HIV drug resistance mutations.
ISSN:1058-4838
1537-6591
DOI:10.1086/597779