Pi-activated alcohols: an emerging class of alkylating agents for catalytic Friedel-Crafts reactions

The direct functionalization of aromatic compounds, via Friedel-Crafts alkylation reactions with alcohols, is one of the cornerstones in organic chemistry. The present emerging area deals with the recent advances in the use of pi-activated alcohols in the catalytic and stereoselective construction o...

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Bibliographic Details
Published in:Organic & biomolecular chemistry 2009-01, Vol.7 (8), p.1501-1507
Main Authors: Bandini, Marco, Tragni, Michele
Format: Article
Language:English
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Summary:The direct functionalization of aromatic compounds, via Friedel-Crafts alkylation reactions with alcohols, is one of the cornerstones in organic chemistry. The present emerging area deals with the recent advances in the use of pi-activated alcohols in the catalytic and stereoselective construction of benzylic stereocenters.
ISSN:1477-0520
1477-0539
DOI:10.1039/b823217b