Nodular regenerative hyperplasia of the liver associated with systemic lupus erythematosus: three cases

Nodular regenerative hyperplasia of the liver, characterised by regenerative nodules distributed throughout the liver in the absence of fibrosis, is a rare but important complication of systemic lupus erythematosus. The main consequence of nodular regenerative hyperplasia of the liver is non-cirrhot...

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Bibliographic Details
Published in:Hong Kong medical journal = Xianggang yi xue za zhi 2009-04, Vol.15 (2), p.139-142
Main Authors: Leung, Vincent K S, Loke, Tony K L, Luk, Ivy S C, Ng, W L, Chau, T N, Law, S T, Chan, James C S
Format: Article
Language:English
Subjects:
Female
Humans
Hyperplasia
Liver - pathology
Liver Regeneration
Lupus
Lupus Erythematosus, Systemic - complications
Lupus Erythematosus, Systemic - pathology
Middle Aged
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Summary:Nodular regenerative hyperplasia of the liver, characterised by regenerative nodules distributed throughout the liver in the absence of fibrosis, is a rare but important complication of systemic lupus erythematosus. The main consequence of nodular regenerative hyperplasia of the liver is non-cirrhotic portal hypertension. This condition is probably underdiagnosed, as many of these patients may remain asymptomatic. Furthermore, nodular regenerative hyperplasia of the liver may be misdiagnosed as cirrhosis. We describe three female patients with nodular regenerative hyperplasia of the liver associated with systemic lupus erythematosus. All three patients have clinical manifestations of portal hypertension, and all were initially misdiagnosed as having cryptogenic cirrhosis.
ISSN:1024-2708
2226-8707