Post-radiotherapy pelvic exenteration in relapsed cervical cancer: experience of a tertiary health service in the northeast of Brazil

to analyze complications, morbidity, mortality and survival rate in a group of patients with cervical cancer with central pelvic relapse after primary radiotherapy treatment. retrospective study of a series of 16 cases of pelvic exenteration after primary radiotherapy treatment. Descriptive statisti...

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Bibliographic Details
Published in:Revista Brasileira de ginecologia e obstetrícia 2009-01, Vol.31 (1), p.22-27
Main Authors: Vieira, Sabas Carlos, Costa, Djalma Ribeiro, Meneses, Aurus Dourado, Borges e Silva, Jeany, Oliveira, Alexandra Kolontai de Sousa, Sousa, Rodrigo Beserra
Format: Article
Language:Portuguese
Subjects:
Adult
Aged
Brazil
Carcinoma, Squamous Cell - mortality
Carcinoma, Squamous Cell - radiotherapy
Carcinoma, Squamous Cell - surgery
Female
Humans
Middle Aged
Multivariate Analysis
Neoplasm Recurrence, Local - mortality
Neoplasm Recurrence, Local - radiotherapy
Neoplasm Recurrence, Local - surgery
Pelvic Exenteration - adverse effects
Pelvic Exenteration - mortality
Prognosis
Regression Analysis
Retrospective Studies
Surgical Wound Infection - etiology
Survival Rate
Urinary Fistula - etiology
Uterine Cervical Neoplasms - mortality
Uterine Cervical Neoplasms - radiotherapy
Uterine Cervical Neoplasms - surgery
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Summary:to analyze complications, morbidity, mortality and survival rate in a group of patients with cervical cancer with central pelvic relapse after primary radiotherapy treatment. retrospective study of a series of 16 cases of pelvic exenteration after primary radiotherapy treatment. Descriptive statistics, survival curve through Kaplan-Meier's method, and regression analysis to evaluate prognosis were performed. sixteen patients have undergone pelvic exenteration. Epidermoid carcinoma, IIb stage and undifferentiated grade were the most frequent conditions. Post-operatory tumor relapse occurred in half the cases. Eleven patients presented peri or post-surgical complications, the most frequent being pelvic infection, that of the surgical wound, and urinary fistulae. Global survival rate was 64.3%, with average follow-up of 11 months. Regression analysis did not detect any significant prognosis factor for the patient survival. the survival rate was 64.3%. No particular factor associated to poor prognosis has been found in the present series of cases.
ISSN:1806-9339
DOI:10.1590/S0100-72032009000100005