The impact of a micro-lightguide spectrophotometer on the intraoperative assessment of hepatic microcirculation: A pilot study

The intraoperative measurement of the peripheral microperfusion after liver transplantation is connected with quite an effort and a continuous evaluation in the postoperative follow up is not possible till now. Before mobilization of the liver during surgical intervention the following parameters we...

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Bibliographic Details
Published in:Microvascular research 2009-05, Vol.77 (3), p.387-388
Main Authors: Ladurner, Ruth, Feilitzsch, Maximilian, Steurer, Wolfgang, Coerper, Stephan, Königsrainer, Alfred, Beckert, Stefan
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Blood Flow Velocity
Hemoglobins - metabolism
Hepatic microcirculation
Humans
Laser-Doppler Flowmetry
Liver - blood supply
Liver Circulation - physiology
Liver Transplantation - physiology
Micro-lightquide spectrophotometer
Microcirculation - physiology
Middle Aged
Monitoring, Intraoperative
Oximetry
Oxygen - blood
Pilot Projects
Positive-Pressure Respiration
Regional Blood Flow
Spectrophotometry - instrumentation
Spectrophotometry - methods
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Summary:The intraoperative measurement of the peripheral microperfusion after liver transplantation is connected with quite an effort and a continuous evaluation in the postoperative follow up is not possible till now. Before mobilization of the liver during surgical intervention the following parameters were measured on the surface of the right (segment 7/8) and the left (segment 2/3) liver lobe with a probe, combining laser-Doppler-flowmetry and tissue-spectrometry: the oxygen saturation (SO2), the relative capillary hemoglobin concentration (rHB), the blood flow (flow) and the blood flow velocity (velo). In addition the peripheral oxygen saturation (SPO2), the central venous pressure (ZVP), the positive endexspiratory pressure (PEEP) and the hemoglobin (HB) were documented. 9 patients (median age 75 years) were included in the study. SPO2, ZVP, PEEP and HB were regular. The parameters SO2, rHB, flow and velo showed no significant changes between the right and the left liver lobe. The O2C-method allows a reproducible intraoperative evaluation of the hepatic microcirculation.
ISSN:0026-2862
1095-9319
DOI:10.1016/j.mvr.2009.01.008