Predictors of Coronary Stent Thrombosis : The Dutch Stent Thrombosis Registry

This study sought to comprehensively identify predictors of stent thrombosis (ST). Given the devastating consequences of ST, efforts should be directed toward risk stratification to identify patients at highest risk for ST. Consecutive patients with angiographic ST were enrolled. Patients who did no...

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Bibliographic Details
Published in:Journal of the American College of Cardiology 2009-04, Vol.53 (16), p.1399-1409
Main Authors: VAN WERKUM, Jochem W, HEESTERMANS, Antonius A, VERHEUGT, Freek W, TEN BERG, Jurriën M, ZOMER, A. Carla, KELDER, Johannes C, SUTTORP, Maarten-Jan, RENSING, Benno J, KOOLEN, Jacques J, GUUS BRUEREN, B. R, DAMBRINK, Jan-Henk E, HAUTVAST, Raymond W
Format: Article
Language:English
Subjects:
Aged
Angina pectoris
Angioplasty, Balloon, Coronary
Biological and medical sciences
Cardiology
Cardiology. Vascular system
Coronary Angiography
Coronary Artery Disease - complications
Coronary heart disease
Coronary Thrombosis - etiology
Coronary vessels
Drug-Eluting Stents - adverse effects
Female
Forecasting
Heart
Heart attacks
Humans
Male
Medical sciences
Middle Aged
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Registries
Risk Assessment
Risk Factors
Stents
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Summary:This study sought to comprehensively identify predictors of stent thrombosis (ST). Given the devastating consequences of ST, efforts should be directed toward risk stratification to identify patients at highest risk for ST. Consecutive patients with angiographic ST were enrolled. Patients who did not suffer from a ST were randomly selected in a 2:1 ratio and were matched for: 1) percutaneous coronary intervention (PCI) indication; 2) same date of index PCI; and 3) same interventional center. Of 21,009 patients treated with either a bare-metal or drug-eluting stent, 437 patients (2.1%) presented with a definite ST. A total of 140 STs were acute, 180 were subacute, 58 were late, and 59 were very late. Undersizing of the coronary stent, Thrombolysis In Myocardial Infarction flow grade
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2008.12.055