Antibiotic resistance of Escherichia coli from community-acquired urinary tract infections. What antimicrobial to use?

Determine antibiotic resistance of community-acquired uropathogen Escherichia coli and infer therapeutic options. E. coli strains isolated from urine during a one-year period were studied. Identification and susceptibility tests were performed. A total of 652 isolates were included from patients in...

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Bibliographic Details
Published in:Salud pública de México 2009-03, Vol.51 (2), p.155-159
Main Authors: Guajardo-Lara, Claudia Elena, González-Martínez, Pedro Mario, Ayala-Gaytán, Juan Jacobo
Format: Article
Language:Spanish
Subjects:
Adult
Ambulatory Care Facilities - statistics & numerical data
Ampicillin - pharmacology
Anti-Bacterial Agents - pharmacology
Anti-Bacterial Agents - therapeutic use
Cefazolin - pharmacology
Ciprofloxacin - pharmacology
Community-Acquired Infections - drug therapy
Community-Acquired Infections - epidemiology
Community-Acquired Infections - microbiology
Drug Resistance, Multiple, Bacterial
Escherichia coli - drug effects
Escherichia coli - genetics
Escherichia coli Infections - drug therapy
Escherichia coli Infections - epidemiology
Escherichia coli Infections - microbiology
Female
Hospitals, Private - statistics & numerical data
Humans
Male
Mexico - epidemiology
Middle Aged
Trimethoprim, Sulfamethoxazole Drug Combination - pharmacology
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Summary:Determine antibiotic resistance of community-acquired uropathogen Escherichia coli and infer therapeutic options. E. coli strains isolated from urine during a one-year period were studied. Identification and susceptibility tests were performed. A total of 652 isolates were included from patients in two institutions, a healthcare clinic 303 (46.5%) and a hospital 349 ( 53.5%). The antimicrobials with higher resistance rates were ampicillin 67.2%, trimethoprim-sulfametoxazole 59.2%, cefazolin 35.6% and ciprofloxacin 24.7%. Resistance to trimethoprim-sulfamethoxazole and ciprofloxacin used for empiric treatment in community urinary infections is high, and there are few available treatment options.
ISSN:1606-7916
DOI:10.1590/S0036-36342009000200012