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Doppler-derived preoperative mitral regurgitation volume predicts postoperative left ventricular dysfunction after mitral valve repair

Background Unexpected postoperative left ventricular (LV) dysfunction after valve repair for mitral regurgitation (MR) occurs in some patients with normal preoperative LV function. Identification of factors that predispose to such LV dysfunction would enhance our understanding of the indications and...

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Bibliographic Details
Published in:The American heart journal 2009-05, Vol.157 (5), p.875-882
Main Authors: Yamano, Tetsuhiro, MD, Gillinov, A. Marc, MD, Wada, Nozomi, MD, Matsumura, Yoshiki, MD, Toyono, Manatomo, MD, Thomas, James D., MD, Shiota, Takahiro, MD
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Language:English
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Summary:Background Unexpected postoperative left ventricular (LV) dysfunction after valve repair for mitral regurgitation (MR) occurs in some patients with normal preoperative LV function. Identification of factors that predispose to such LV dysfunction would enhance our understanding of the indications and outcomes of surgery. Methods We retrospectively analyzed pre- and postoperative (median fourth day) echocardiograms of 174 patients undergoing valve repair for pure and isolated MR. Preoperative MR volume was quantified by the quantitative Doppler and/or proximal isovelocity surface area method. Results There was an incremental predictive value of MR quantification over the current recommendations (global χ2 from 48.14 to 81.57, P < .001; Hosmer-Lemeshow test, P = .98), for postoperative LV dysfunction, defined as ejection fraction
ISSN:0002-8703
1097-6744
DOI:10.1016/j.ahj.2009.03.001