Experimental transplacental infection of sheep with bluetongue virus serotype 8

Transplacental transmission of wild-type BTV-8 was confirmed in fetus 2, which was rRT-PCR-positive. Because no precolostral plasma was available, only the results of samples taken after colostrum uptake can be considered in assessing whether the lamb was infected with BTV-8 in utero ( Fig 2 ). In w...

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Bibliographic Details
Published in:Veterinary record 2009-04, Vol.164 (16), p.499-500
Main Authors: Worwa, G., Hilbe, M., Ehrensperger, F., Chaignat, V., Hofmann, M. A., Griot, C., Maclachlan, N. J., Thuer, B.
Format: Article
Language:English
Subjects:
Animals
Animals, Newborn
Bluetongue - pathology
Bluetongue - transmission
Bluetongue - virology
Bluetongue virus
Bluetongue virus - classification
Cell culture
Cercopithecus aethiops
Epidemics
Female
Fetus - virology
Fetuses
Immunoglobulins
Infections
Infectious Disease Transmission, Vertical - veterinary
Lymphatic system
Maternal-Fetal Exchange
Neutralization Tests
Plasma
Pregnancy
Sheep
transplacental transmission
Vero Cells
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Summary:Transplacental transmission of wild-type BTV-8 was confirmed in fetus 2, which was rRT-PCR-positive. Because no precolostral plasma was available, only the results of samples taken after colostrum uptake can be considered in assessing whether the lamb was infected with BTV-8 in utero ( Fig 2 ). In white-tailed deer, maternal neutralising antibodies to BTV and epizootic haemorrhagic disease virus persisted until 17 to 18 weeks of age ( Gaydos and others 2002 ). [...]it is possible that the detected antibodies in the lamb at day 73 could still be maternal in origin.
ISSN:0042-4900
2042-7670
DOI:10.1136/vr.164.16.499