Hippocampal changes and white matter lesions in early-onset depression

Hippocampal volume reduction and increased prevalence of subcortical white matter lesions have been reported in late-life depression. We aimed to examine whether total number of subcortical white matter lesions were associated with reduced hippocampal volume in aged female subjects with early-onset...

Full description

Saved in:
Bibliographic Details
Published in:Biological psychiatry (1969) 2004-12, Vol.56 (11), p.825-831
Main Authors: Janssen, Joost, Hulshoff Pol, Hilleke E., Lampe, Indrag K., Schnack, Hugo G., de Leeuw, Frank-Erik, Kahn, Rene S., Heeren, Thea J.
Format: Article
Language:English
Subjects:
Adult and adolescent clinical studies
Age of Onset
Aged
Aged, 80 and over
Analysis of Variance
Biological and medical sciences
Case-Control Studies
Depression
Depression - pathology
Depression - physiopathology
Female
Frontal Lobe - pathology
Functional Laterality
hippocampus
Hippocampus - pathology
Humans
Linear Models
Magnetic Resonance Imaging - methods
Medical sciences
Middle Aged
Mood disorders
MRI
orbitofrontal cortex
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Reproducibility of Results
white matter lesions
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Hippocampal volume reduction and increased prevalence of subcortical white matter lesions have been reported in late-life depression. We aimed to examine whether total number of subcortical white matter lesions were associated with reduced hippocampal volume in aged female subjects with early-onset depression (
ISSN:0006-3223
1873-2402
DOI:10.1016/j.biopsych.2004.09.011