Utilization of the auditory consonant trigram test to screen for cognitive impairment in patients with multiple sclerosis: comparison with the paced auditory serial addition test

Several screening methods have been evaluated, but most of them are insensitive to MS-related cognitive impairment. The Auditory Consonant Trigram (ACT) test, which contains core features required for a working memory task, has been used to test neuro-cognitive function in different samples of patie...

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Bibliographic Details
Published in:Multiple sclerosis 2004-12, Vol.10 (6), p.686-689
Main Authors: Ozakbas, S, Ormeci, B, Akdede, B B.Kivircik, Alptekin, K, Idiman, E
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Cognition Disorders - diagnosis
Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
Evaluation Studies as Topic
Female
Humans
Immunomodulators
Male
Mass Screening - methods
Medical sciences
Memory, Short-Term
Middle Aged
Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis
Multiple Sclerosis, Relapsing-Remitting - diagnosis
Multiple Sclerosis, Relapsing-Remitting - psychology
Neurology
Neuropsychological Tests
Pharmacology. Drug treatments
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Summary:Several screening methods have been evaluated, but most of them are insensitive to MS-related cognitive impairment. The Auditory Consonant Trigram (ACT) test, which contains core features required for a working memory task, has been used to test neuro-cognitive function in different samples of patients to examine the status of working memory. The aim of the present study was to investigate the correlation between ACT and the Paced Auditory Serial Addition Test (PASAT), and the usefulness of ACT for evaluating the cognitive impairment in MS in a brief visit. A total of 109 consecutive patients with definite MS were included. The patients were administered ACT, PASAT and EDSS. Mean PASAT score and mean ACT score were 46.199-8.51 and 45.309-9.07, respectively. Correlations between EDSS and PASAT, and EDSS and ACTwere moderately strong. The correlation between ACT and PASATwas very strong (r=0.831, P
ISSN:1352-4585
1477-0970
DOI:10.1191/1352458504ms1111oa