A systematic review on outcome after stenting for intracranial atherosclerosis

Angioplasty and stenting is increasingly being used for the treatment of intracranial stenoses. Based on a literature search (01/1998 to 04/2008) we sought to determine the immediate and long-term outcomes, as well as the durability of this procedure. We identified 31 studies dealing with 1177 proce...

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Bibliographic Details
Published in:Stroke (1970) 2009-05, Vol.40 (5), p.e340-e347
Main Authors: Gröschel, Klaus, Schnaudigel, Sonja, Pilgram, Sara M, Wasser, Katrin, Kastrup, Andreas
Format: Article
Language:English
Subjects:
Aged
Angioplasty
Atherosclerosis - surgery
Cerebrovascular Disorders - surgery
Data Interpretation, Statistical
Female
Follow-Up Studies
Humans
Male
Middle Aged
Stents
Treatment Outcome
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Summary:Angioplasty and stenting is increasingly being used for the treatment of intracranial stenoses. Based on a literature search (01/1998 to 04/2008) we sought to determine the immediate and long-term outcomes, as well as the durability of this procedure. We identified 31 studies dealing with 1177 procedures, which had mainly been performed in patients with a symptomatic (98%) intracranial high-grade stenosis (mean: 78+/-7%) at high technical success rates (median: 96%; interquartile range [IQR]: 90% to 100%). The periprocedural minor or major stroke and death rates ranged from 0% to 50% with a median of 7.7% (IQR: 4.4% to 14.3%). Periprocedural complications were significantly higher in the posterior versus the anterior circulation (12.1%, versus 6.6%, P50% occurred more frequently after the use of a self-expandable stent (16/92; 17.4%, mean follow-up time: 5.4 months) than a balloon-mounted stent (61/443; 13.8%, mean follow-up time: 8.7 months; P
ISSN:0039-2499
1524-4628
DOI:10.1161/STROKEAHA.108.532713