Dielectric modulation of biological water

We show that water constrained by vicinal hydrophobes undergoes a librational dynamics that lowers the dielectric susceptibility and induces a "redshift" of the relaxation frequency in the hydration shell. The results shed light on the way proteins enhance their intramolecular interactions...

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Bibliographic Details
Published in:Physical review letters 2004-11, Vol.93 (22), p.228104-228104, Article 228104
Main Authors: Despa, Florin, Fernández, Ariel, Berry, R Stephen
Format: Article
Language:English
Subjects:
Body Water - chemistry
Computer Simulation
Electric Conductivity
Models, Chemical
Models, Molecular
Molecular Conformation
Protein Conformation
Protein Folding
Proteins - chemistry
Static Electricity
Water - chemistry
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Summary:We show that water constrained by vicinal hydrophobes undergoes a librational dynamics that lowers the dielectric susceptibility and induces a "redshift" of the relaxation frequency in the hydration shell. The results shed light on the way proteins enhance their intramolecular interactions as they fold or associate.
ISSN:0031-9007
1079-7114
DOI:10.1103/PhysRevLett.93.228104