Impact of Gender and Age on In Vivo Virtual Histology–Intravascular Ultrasound Imaging Plaque Characterization (from the global Virtual Histology Intravascular Ultrasound [VH-IVUS] Registry)

Virtual histology intravascular ultrasound (VH-IVUS) analyses were performed in the first 990 patients enrolled in the 3,000+ patient global VH-IVUS Registry to assess the impact of gender and age on in vivo VH-IVUS plaque characterization. The 990 patients were divided into 3 age group terciles (68...

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Bibliographic Details
Published in:The American journal of cardiology 2009-05, Vol.103 (9), p.1210-1214
Main Authors: Qian, Jie, MD, Maehara, Akiko, MD, Mintz, Gary S., MD, Margolis, M. Pauliina, MD, PhD, Lerman, Amir, MD, Rogers, Jason, MD, Banai, Shuel, MD, Kazziha, Samer, MD, Castellanos, Celia, MD, Dani, Lokesh, BS, Fahy, Martin, MSc, Stone, Gregg W., MD, Leon, Martin B., MD
Format: Article
Language:English
Subjects:
Age
Age Factors
Aged
Analysis of Variance
Biological and medical sciences
Biopsy, Needle
Cardiology
Cardiology. Vascular system
Cardiovascular
Coronary Artery Disease - diagnostic imaging
Coronary Artery Disease - epidemiology
Coronary Artery Disease - pathology
Female
Gender
Heart
Histology
Humans
Immunohistochemistry
Incidence
Investigative techniques, diagnostic techniques (general aspects)
Male
Medical sciences
Middle Aged
Miscellaneous. Technology
Multivariate Analysis
Probability
Prognosis
Registries
Risk Assessment
Sensitivity and Specificity
Severity of Illness Index
Sex Factors
Survival Analysis
Ultrasonic imaging
Ultrasonic investigative techniques
Ultrasonography, Interventional
User-Computer Interface
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Summary:Virtual histology intravascular ultrasound (VH-IVUS) analyses were performed in the first 990 patients enrolled in the 3,000+ patient global VH-IVUS Registry to assess the impact of gender and age on in vivo VH-IVUS plaque characterization. The 990 patients were divided into 3 age group terciles (68 years) and again divided according to gender. In conclusion, (1) both women and men had an increase in plaque with increasing age; (2) at any age, men had more plaque than women; (3) percentages of dense calcium and necrotic core increased with increasing patient age in both men and women; and (4) gender differences were lowest in the oldest tercile (>68 years).
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2009.01.031