Is a history of gestational diabetes related to risk factors for coronary heart disease?

Coronary heart disease (CHD) risk in 20 non‐diabetic women with and 20 without a distant history of gestational diabetes (hGDM), matched on age, body mass index, and time since GDM‐affected pregnancy, was compared in a case control study. Women with an hGDM had lower high‐density lipoprotein cholest...

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Bibliographic Details
Published in:Research in nursing & health 2009-06, Vol.32 (3), p.298-306
Main Authors: King, Kathleen B., Gerich, John E., Guzick, David S., King, Kathleen U., McDermott, Michael P.
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Cardiology. Vascular system
Cardiovascular disease
cardiovascular risk
Case-Control Studies
Chi-Square Distribution
Cholesterol
Cholesterol - blood
Cholesterol, HDL - blood
Coronary Disease - blood
Coronary Disease - epidemiology
Coronary Disease - etiology
Coronary diseases
Coronary heart disease
Diabetes
Diabetes Complications - blood
Diabetes Complications - complications
Diabetes Complications - epidemiology
Diabetes Mellitus, Type 2 - etiology
Diabetes, Gestational - blood
Diabetes, Gestational - epidemiology
Diabetes, Gestational - etiology
Distant
Female
gestational diabetes
Gestational diabetes mellitus
Glucose
Heart
Heart diseases
Humans
Logistic Models
Medical sciences
Middle Aged
Miscellaneous
Multivariate Analysis
Nursing
Obesity - complications
Prediabetic State - etiology
Pregnancy
Public health. Hygiene
Public health. Hygiene-occupational medicine
Risk Assessment
Risk Factors
Time Factors
Triglycerides - blood
Women
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Summary:Coronary heart disease (CHD) risk in 20 non‐diabetic women with and 20 without a distant history of gestational diabetes (hGDM), matched on age, body mass index, and time since GDM‐affected pregnancy, was compared in a case control study. Women with an hGDM had lower high‐density lipoprotein cholesterol (HDL‐c), p = .02, and higher triglycerides, p ≤ .001, versus controls. The combination of high triglycerides and low HDL‐c occurred in 25% of hGDM cases versus 0% of controls, p ≤ .01. Two‐hour post‐load glucose indicated that 45% of hGDM cases were pre‐diabetic versus 20% of controls, p ≤ .05. Non‐diabetic women with a distant hGDM are at increased risk for DM and may be at increased risk for CHD. © 2009 Wiley Periodicals, Inc. Res Nurs Health 32:298–306, 2009
ISSN:0160-6891
1098-240X
DOI:10.1002/nur.20325