Upper Gastrointestinal Symptoms and Associated Disorders in Morbidly Obese Patients: A Prospective Study

Objective To prospectively evaluate the frequency of upper gastrointestinal symptoms and associated disorders in morbidly obese patients with endoscopy and histology prior to their gastric bypass surgery in comparison with age- and sex-matched nonobese control subjects. Methods All patients who were...

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Bibliographic Details
Published in:Digestive diseases and sciences 2009-06, Vol.54 (6), p.1243-1246
Main Authors: Dutta, Sudhir K., Arora, Manish, Kireet, Agrawal, Bashandy, Hany, Gandsas, Alejandro
Format: Article
Language:English
Subjects:
Adult
Biochemistry
Biological and medical sciences
Feeding. Feeding behavior
Female
Fundamental and applied biological sciences. Psychology
Gastritis - complications
Gastroenterology
Heartburn - complications
Helicobacter pylori
Hepatology
Hernia, Hiatal - complications
Humans
Male
Medical sciences
Medicine
Medicine & Public Health
Metabolic diseases
Middle Aged
Obesity
Obesity, Morbid - complications
Oncology
Original Article
Transplant Surgery
Vertebrates: anatomy and physiology, studies on body, several organs or systems
Young Adult
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Summary:Objective To prospectively evaluate the frequency of upper gastrointestinal symptoms and associated disorders in morbidly obese patients with endoscopy and histology prior to their gastric bypass surgery in comparison with age- and sex-matched nonobese control subjects. Methods All patients who were scheduled to undergo laparoscopic gastric bypass for treatment of morbid obesity (body mass index, BMI > 40 kg/m 2 ) during a 1-year period ( n  = 101) were included in the study. Age- and sex-matched nonobese patients who were seen in the medical clinics during the study period were enrolled as control subjects. The demographic data, total body weight, body mass index, and gastrointestinal symptoms were recorded, and the results of upper endoscopy and histology were tabulated. Endoscopic documentation of hiatal hernia, esophagitis, gastritis, gastric polyps, and peptic ulcer disease was also noted along with the histologic findings of the mucosal biopsies from the upper gastrointestinal tract. Results The prevalence of heartburn as a symptom was significantly higher ( P  
ISSN:0163-2116
1573-2568
DOI:10.1007/s10620-008-0485-6