Aging: Shall We Take the High Road?

For ectotherms, lifespan is increased at low temperature and decreased at high temperature. A new study in Caenorhabditis elegans shows that thermosensory neurons can counteract the effects of high temperature on lifespan by controlling the activity of a steroid signaling pathway.

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Bibliographic Details
Published in:Current biology 2009-05, Vol.19 (9), p.R363-R364
Main Authors: Mori, Ikue, Sasakura, Hiroyuki
Format: Article
Language:English
Subjects:
Aging - physiology
Animals
Caenorhabditis elegans - physiology
Longevity - physiology
Models, Biological
Temperature
Thermoreceptors - physiology
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Description
Summary:For ectotherms, lifespan is increased at low temperature and decreased at high temperature. A new study in Caenorhabditis elegans shows that thermosensory neurons can counteract the effects of high temperature on lifespan by controlling the activity of a steroid signaling pathway.
ISSN:0960-9822
1879-0445
DOI:10.1016/j.cub.2009.03.040