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Comparison of sonographically measured bowel wall vascularity, histology, and disease activity in Crohn’s disease

The purposes of this study was to provide a retrospective comparison of semiquantitatively measured bowel wall vascularity by power Doppler sonography, endoscopic-histopathological biopsy findings, and disease activity in patients with confirmed Crohn’s disease. Thirty-two out of 1,332 patients with...

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Bibliographic Details
Published in:European radiology 2009-06, Vol.19 (6), p.1379-1386
Main Authors: Drews, B. H., Barth, T. F. E., Hänle, M. M., Akinli, A. S., Mason, R. A., Muche, R., Thiel, R., Pauls, S., Klaus, J., von Boyen, G., Kratzer, W.
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Language:English
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Summary:The purposes of this study was to provide a retrospective comparison of semiquantitatively measured bowel wall vascularity by power Doppler sonography, endoscopic-histopathological biopsy findings, and disease activity in patients with confirmed Crohn’s disease. Thirty-two out of 1,332 patients with histologically confirmed Crohn’s disease (18 female, 14 male; mean age 38.8 years) met the inclusion criteria: ileocolonoscopy with biopsy and power Doppler sonographic determination of bowel wall vascularity with assessment of disease activity within a period of 5 days. Sonographic determination of bowel wall vascularity was based on a semiquantitative score. Endoscopic bowel wall biopsy specimens were assessed using a self-developed inflammation score and the disease activity was calculated using Crohn’s disease activity index (CDAI). A significant association ( p  
ISSN:0938-7994
1432-1084
DOI:10.1007/s00330-008-1290-5