Transplantation of cultured human neural stem cells in rabbits with experimental laser-induced damage to the retina

Cultured neural stem/progenitor cells from human fetal brain were transplanted into the retrobulbar and suprachoroid space in rabbits with laser-induced damage to the retina. Transplanted cells survived, retained multipotent activity, migrated into the zone of injury, and stimulated reparation and r...

Full description

Saved in:
Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2004-11, Vol.138 (5), p.525-528
Main Authors: Pak, N V, Podgornyi, O V, Aleksandrova, M A, Chentsova, E V, Ivanov, A N, Golubeva, O N, Poltavtseva, R A, Marey, M V, Sukhikh, G T
Format: Article
Language:English
Subjects:
Animals
Eye Injuries - surgery
Humans
Lasers
Rabbits
Retina - pathology
Retina - radiation effects
Stem Cell Transplantation - methods
Transplantation, Heterologous
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Cultured neural stem/progenitor cells from human fetal brain were transplanted into the retrobulbar and suprachoroid space in rabbits with laser-induced damage to the retina. Transplanted cells survived, retained multipotent activity, migrated into the zone of injury, and stimulated reparation and regeneration in the traumatized retina.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-005-0087-7