Clinically suspected acute pulmonary embolism: a comparison of presentation, radiological features and outcome in patients with and without PE

Background: Relatively little is known about prognosis in patients for whom suspected pulmonary embolism (PE) is refuted by imaging. Aim: This prospective study of suspected PE therefore compared clinico-radiological features and outcome in patients with and without PE. Design and Methods: Computed...

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Bibliographic Details
Published in:QJM : An International Journal of Medicine 2009-06, Vol.102 (6), p.407-414
Main Authors: Akram, A.R., Cowell, G.W., Logan, L.J.A., Macdougall, M., Reid, J.H., Murchison, J.T., Simpson, A.J.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Biological and medical sciences
Comorbidity
Epidemiologic Methods
Female
General aspects
Humans
Male
Medical sciences
Middle Aged
Pneumology
Prospective Studies
Pulmonary Artery - diagnostic imaging
Pulmonary Embolism - diagnosis
Pulmonary Embolism - diagnostic imaging
Pulmonary Embolism - mortality
Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases
Radiography
Treatment Outcome
Young Adult
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Summary:Background: Relatively little is known about prognosis in patients for whom suspected pulmonary embolism (PE) is refuted by imaging. Aim: This prospective study of suspected PE therefore compared clinico-radiological features and outcome in patients with and without PE. Design and Methods: Computed tomographic pulmonary angiography (CTPA) confirmed or refuted PE in consecutive patients. Clinical, laboratory and radiological features were recorded at baseline, and mortality at 1 year determined. Univariate and multivariate analyses identified variables associated with PE. Results: PE was diagnosed in 45 patients and refuted in 141. The PE and ‘non-PE’ groups were similar with regard to extravascular radiology (though consolidation was significantly more common in the PE group [present in 24 (53%) of the PE group and 42 (30%) of the non-PE group, P 
ISSN:1460-2725
1460-2393
DOI:10.1093/qjmed/hcp041