Accuracy of Transcranial Doppler Compared With CT Angiography in Diagnosing Arterial Obstructions in Acute Ischemic Strokes

Patients with acute ischemic stroke and intracranial arterial obstructions have a poor prognosis and a high probability of deteriorating at 24 hours. We aimed to evaluate the diagnostic accuracy of power motion mode Doppler (PMD-TCD) compared with CT angiography as standard in diagnosing intracrania...

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Bibliographic Details
Published in:Stroke (1970) 2009-06, Vol.40 (6), p.2037-2041
Main Authors: BRUNSER, Alejandro M, LAVADOS, Pablo M, HOPPE, Arnold, LOPEZ, Javiera, VALENZUELA, Marcela, RIVAS, Rodrigo
Format: Article
Language:English
Subjects:
Acute Disease
Adult
Aged
Aged, 80 and over
Algorithms
Biological and medical sciences
Brain Ischemia - diagnosis
Brain Ischemia - diagnostic imaging
Cerebral Angiography
Cerebral Arterial Diseases - diagnosis
Cerebral Arterial Diseases - diagnostic imaging
False Negative Reactions
False Positive Reactions
Female
Humans
Investigative techniques, diagnostic techniques (general aspects)
Likelihood Functions
Male
Medical sciences
Middle Aged
Middle Cerebral Artery - diagnostic imaging
Nervous system
Neurology
Reproducibility of Results
Stroke - diagnosis
Stroke - diagnostic imaging
Tomography, X-Ray Computed
Ultrasonic investigative techniques
Ultrasonography, Doppler, Transcranial
Vascular diseases and vascular malformations of the nervous system
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Summary:Patients with acute ischemic stroke and intracranial arterial obstructions have a poor prognosis and a high probability of deteriorating at 24 hours. We aimed to evaluate the diagnostic accuracy of power motion mode Doppler (PMD-TCD) compared with CT angiography as standard in diagnosing intracranial arterial obstructions in patients presenting with ischemic stroke of 1000, negative likelihood ratio 0.42, sensitivity 57.1%, and specificity 100%. The post-test probability for any occluded artery when PMD-TCD was positive increased for any admission National Institutes of Health Stroke Scale score but was especially remarkable for National Institutes of Health Stroke Scale scores between 7 and 15 points. PMD-TCD is valid compared with CT angiography for the diagnosis of arterial occlusions in patients with acute ischemic stroke, especially in middle cerebral artery obstructions.
ISSN:0039-2499
1524-4628
DOI:10.1161/STROKEAHA.108.542704