Acute subarachnoid hemorrhage associated with platelet storage pool disease and the hemoglobinopathy caused by beta-thalassemia minor

We describe a case of acute subarachnoid hemorrhage with a complex blood-clotting mechanism and two negative angiographies. The patient was discharged from hospital with a presumptive diagnosis of idiopathic causes, but further analysis of the clinical history from the primary care provider prompted...

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Bibliographic Details
Published in:Journal of stroke and cerebrovascular diseases 2004-09, Vol.13 (5), p.189-191
Main Authors: Ortega-Calvo, Manuel, Sosa-Alamo, Roberto, Mayol-Deyá, Antonio
Format: Article
Language:English
Subjects:
platelet aggregation
storage pool disease
Subarachnoid hemorrhage
thalassemia minor
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Summary:We describe a case of acute subarachnoid hemorrhage with a complex blood-clotting mechanism and two negative angiographies. The patient was discharged from hospital with a presumptive diagnosis of idiopathic causes, but further analysis of the clinical history from the primary care provider prompted a hematologic analysis, which produced a diagnosis of platelet storage pool disease with alterations during the degranulation and aggregation functions. Electron microscopy revealed no ultrastructural abnormalities of platelet membranes, granules, or organelles. The patient had been previously diagnosed with thalassemia minor.
ISSN:1052-3057
1532-8511
DOI:10.1016/j.jstrokecerebrovasdis.2004.07.003