Low-frequency and high-intensity ultrasonic may play a better role in Ultrasound Contrast Agent drug delivery system in vivo

Summary For the ability to carry drugs and release them at target areas, Ultrasound Contrast Agent (UCA) can be a new vector for drug delivery. Ultrasound makes UCA ruptured so that the drugs it carried can be released. The intensity of medical ultrasound varies wildly. Although low-intensity ultras...

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Bibliographic Details
Published in:Medical hypotheses 2009-08, Vol.73 (2), p.211-212
Main Authors: Zhu, Jia-an, Hu, Yi-zhou, Jiang, Ye-qing, Xing, Chun-yan, Li, Dian-cheng, Hu, Bing
Format: Article
Language:English
Subjects:
Contrast Media
Drug Delivery Systems
Internal Medicine
Ultrasonics
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Summary:Summary For the ability to carry drugs and release them at target areas, Ultrasound Contrast Agent (UCA) can be a new vector for drug delivery. Ultrasound makes UCA ruptured so that the drugs it carried can be released. The intensity of medical ultrasound varies wildly. Although low-intensity ultrasound is often used in vitro studies, we think in vivo, the application of high-intensity ultrasound will have better future prospects for drug delivery than low-intensity ultrasonic.
ISSN:0306-9877
1532-2777
DOI:10.1016/j.mehy.2009.02.014