Encapsulation and Sustained Release of Curcumin using Superparamagnetic Silica Reservoirs

For controlled release and targeted delivery of curcumin in an aqueous medium a method of encapsulating curcumin and magnetic nanoparticles inside porous silica matrix has been developed. Curcumin and superparamagnetic nanoparticles are loaded inside porous silica in a single process. The graphic sh...

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Bibliographic Details
Published in:Chemistry : a European journal 2009-06, Vol.15 (23), p.5661-5665
Main Authors: Chin, Suk Fun, Iyer, K. Swaminathan, Saunders, Martin, St. Pierre, Tim G., Buckley, Craig, Paskevicius, Mark, Raston, Colin L.
Format: Article
Language:English
Subjects:
curcumin
Curcumin - administration & dosage
drug delivery
Drug Delivery Systems
Ferric Compounds - chemical synthesis
Ferric Compounds - chemistry
Nanoparticles - therapeutic use
silica capsule
Silicon Dioxide - chemistry
superparamagnetics
sustained release
Water
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Summary:For controlled release and targeted delivery of curcumin in an aqueous medium a method of encapsulating curcumin and magnetic nanoparticles inside porous silica matrix has been developed. Curcumin and superparamagnetic nanoparticles are loaded inside porous silica in a single process. The graphic shows the TEM image of microtomed sample of Fe3O4 particles surrounded by a silica matrix. For controlled release and targeted delivery of curcumin in an aqueous medium a method of encapsulating curcumin and magnetic nanoparticles inside porous silica matrix has been developed. Curcumin and superparamagnetic nanoparticles are loaded inside porous silica in a single process. The graphic shows the TEM image of microtomed sample of Fe3O4 particles surrounded by a silica matrix.
ISSN:0947-6539
1521-3765
DOI:10.1002/chem.200802747