Levels of lipid peroxidation, nitric oxide, and antioxidant vitamins in plasma of patients with fibromyalgia

The etiology of fibromyalgia is not clearly understood. In recent years, a few studies have investigated the possible role of reactive oxygen species (ROS) in the etiology and pathogenesis of fibromyalgia. The aim of this study was to investigate plasma antioxidant vitamins, lipid peroxidation (LP),...

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Bibliographic Details
Published in:Cell biochemistry and function 2009-06, Vol.27 (4), p.181-185
Main Authors: Akkuş, Selami, Nazıroğlu, Mustafa, Eriş, Sevilay, Yalman, Kadir, Yılmaz, Nigar, Yener, Mahmut
Format: Article
Language:English
Subjects:
Adult
antioxidant redox system
Antioxidants - analysis
Ascorbic Acid - blood
beta Carotene - blood
Female
fibromyalgia
Fibromyalgia - blood
Fibromyalgia - etiology
Humans
Lipid Peroxidation
local ischemia
Middle Aged
Nitric Oxide - blood
oxidative stress
Reactive Nitrogen Species - metabolism
Vitamin A - blood
vitamin E
Vitamin E - blood
Vitamins - blood
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Summary:The etiology of fibromyalgia is not clearly understood. In recent years, a few studies have investigated the possible role of reactive oxygen species (ROS) in the etiology and pathogenesis of fibromyalgia. The aim of this study was to investigate plasma antioxidant vitamins, lipid peroxidation (LP), and nitric oxide (NO) levels in patients with fibromyalgia and controls. The study was performed on the blood plasma of 30 female patients and 30 age‐matched controls. After a fast of 12 h, blood samples were taken, and plasma samples were obtained for measurement of vitamins A, C, E, and β‐carotene concentrations and levels of LP and NO. Concentrations of vitamins A (p 
ISSN:0263-6484
1099-0844
DOI:10.1002/cbf.1548