RNA-mediated chromatin-based silencing in plants

Plants have evolved an elaborate transcriptional machinery dedicated to eliciting sequence-specific, chromatin-based gene silencing. Two Pol II-related, plant-specific RNA polymerases, named Pol IV and Pol V, collaborate with proteins of the RNA interference machinery to generate long and short nonc...

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Bibliographic Details
Published in:Current opinion in cell biology 2009-06, Vol.21 (3), p.367-376
Main Authors: Matzke, Marjori, Kanno, Tatsuo, Daxinger, Lucia, Huettel, Bruno, Matzke, Antonius JM
Format: Article
Language:English
Subjects:
DNA Methylation
DNA, Plant - chemistry
DNA, Plant - genetics
DNA, Plant - metabolism
DNA-Directed RNA Polymerases - genetics
DNA-Directed RNA Polymerases - metabolism
Gene Silencing
Internal Medicine
Plants - genetics
Plants - metabolism
RNA Interference
RNA, Untranslated - genetics
RNA, Untranslated - metabolism
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Summary:Plants have evolved an elaborate transcriptional machinery dedicated to eliciting sequence-specific, chromatin-based gene silencing. Two Pol II-related, plant-specific RNA polymerases, named Pol IV and Pol V, collaborate with proteins of the RNA interference machinery to generate long and short noncoding RNAs involved in epigenetic regulation. As revealed by a variety of genetic, molecular, and genomic technologies, these RNAs are used extensively in plants to direct the establishment, spread, and removal of DNA cytosine methylation throughout their genomes. RNA-mediated chromatin-level silencing is increasingly implicated in development, stress responses, and natural epigenetic variation that may promote phenotypic diversity, physiological plasticity, and evolutionary change.
ISSN:0955-0674
1879-0410
DOI:10.1016/j.ceb.2009.01.025