Serum and follicular resistin levels in women with polycystic ovarian syndrome during IVF-stimulated cycles

BACKGROUND: Resistin is a hormone linking obesity and insulin resistance. The aim of this study was to compare resistin levels in serum or follicular fluid from women with polycystic ovarian syndrome (PCOS) and controls, both of whom were undergoing IVF. METHODS: We compared serum and follicular res...

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Published in:Human reproduction (Oxford) 2005-01, Vol.20 (1), p.117-121
Main Authors: Seow, Kok-Min, Juan, Chi-Chang, Hsu, Yung-Pei, Ho, Low-Tone, Wang, Yuan-Yung, Hwang, Jiann-Loung
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Case-Control Studies
Female
Fertilization in Vitro
follicular fluid
Follicular Fluid - metabolism
Gynecology. Andrology. Obstetrics
Hormones, Ectopic - blood
Hormones, Ectopic - metabolism
Humans
Infertility, Female - blood
Infertility, Female - metabolism
Infertility, Female - therapy
Insulin Resistance
IVF
Medical sciences
polycystic ovarian syndrome
Polycystic Ovary Syndrome - blood
Polycystic Ovary Syndrome - metabolism
Polycystic Ovary Syndrome - therapy
Pregnancy
Pregnancy Outcome
Resistin
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Summary:BACKGROUND: Resistin is a hormone linking obesity and insulin resistance. The aim of this study was to compare resistin levels in serum or follicular fluid from women with polycystic ovarian syndrome (PCOS) and controls, both of whom were undergoing IVF. METHODS: We compared serum and follicular resistin levels in 21 PCOS women and in 18 healthy, normal ovulation, age- and body mass index (BMI)-matched non-PCOS women undergoing IVF. Correlations between serum or follicular fluid resistin levels and reproductive outcome were evaluated. RESULTS: There was no significant difference in either serum or follicular resistin levels between the control group and the PCOS group as a whole or those with insulin resistance [homeostasis model assessment of insulin resistance index applied to oral glucose tolerance test (HOMAOGTT)
ISSN:0268-1161
1460-2350
DOI:10.1093/humrep/deh589